Tyler Meldrum, CV

Education

• Ph.D. in Chemistry from the University of California, Berkeley, 2006-2011
• B.S. in Biochemistry from Brigham Young University, 2004-2006
• University of Colorado, Boulder, 1999-2001

Academic positions

• 2020-
  • Associate Professor of Chemistry at William & Mary
• 2013-2020
  • Assistant Professor of Chemistry at William & Mary
• 2011-2013
  • Alexander von Humboldt Research Fellow
  • RWTH University (Aachen, Germany)
• 2010
  • Adjunct lecturer
  • Contra Costa Community College (San Pablo, CA)

Courses taught

• Physical Chemistry I (CHEM 301: quantum mechanics and spectroscopy)
  • 2021, 50 students
• Physical Chemistry II (CHEM 302: thermodynamics, statistical mechanics, and kinetics)
  • 2017-2020, ~200 students
• Physical Chemistry Lab
  • 2013-2021
• General Chemistry I
  • 2013-2015, ~400 students
• Physical/Analytical Chemistry for Life Sciences (CHEM 341)
  • 2015-2017, 2019

Funded fellowships and grants

• 2021
  • United States-Israel Binational Science Foundation
  • Metals, magnets, and microwaves: Enhancing single-sided NMR signals in materials with DNP
    • Joint proposal with Dr. Daphna Shimon, Hebrew University of Jerusalem
    • Total two-year funding (Feb 2022–Jan 2024): \$150,000; W&M portion: \$75,000
• 2020
  • Small Business Technology Transfer (STTR) Sequential Phase II Grant
  • Method for Locally Measuring Strength of a Polymer-Inorganic Interface During Cure and Aging
  • Cooperative project between Metna Co. (Lansing, MI), Rutgers University (Newark, NJ), and William & Mary.
    • Oct 2020–Sept 2022; Total funding: \$1,100,000. W&M portion: \$165,000
• 2018
  • Small Business Technology Transfer (STTR) Phase II Grant
  • Method for Locally Measuring Strength of a Polymer-Inorganic Interface During Cure and Aging
  • Cooperative project between Metna Co. (Lansing, MI), Rutgers University (Newark, NJ), and William & Mary.
    • Oct 2018–Dec 2020; Total funding: \$1,000,000. W&M portion: \$150,000
• 2016
  • Faculty Summer Research Grant (internal funding)
    • Awarded for Summer 2017
• 2015
  • Colonial Williamsburg Foundation
    • Summer stipend for undergraduate research student; focus on analysis of dyed textiles
    • Summer 2015; \$3450
• 2014
  • Faculty Summer Research Grant (internal funding)
    • Awarded for Summer 2014
• 2014
  • American Chemical Society Petroleum Research Fund, Undergraduate New Investigator Proposal:
  • Investigating the Development of Intermolecular Networks in Coatings with Single-sided NMR
    • Awarded October 2014; \$55,000

Funding

Metals, magnets, and microwaves: Enhancing single-sided NMR signals in materials with DNP

Method for Locally Measuring Strength of a Polymer-Inorganic Interface During Cure and Aging

Method for Locally Measuring Strength of a Polymer-Inorganic Interface During Cure and Aging

Faculty Summer Research Grant

Colonial Williamsburg Foundation

Investigating the Development of Intermolecular Networks in Coatings with Single-sided NMR

Faculty Summer Research Grant

Publications

Underlined student names are undergraduate coauthors. Boldface student names are graduate student coauthors.

20. Characterization of molecular environments and chemical exchange in acrylic paints via single-sided NMR

Lyndi Kiple, Tyler Lee, Gillian Zavaglia, Tyler Meldrum. Prog. Org. Coat. 2023, 183, 107770.

19. Automated optimization of spatial resolution for single-sided NMR

Lyndi Kiple, Jack Ballenger, Kristina Keating, Anagi Balachandra, Tyler Meldrum. Magn. Reson. Chem. 2023, 61(7), 418–426.

18. Effect of pigment concentration on NMR relaxometry in acrylic paints

Rooney, M. T.; Meldrum, T. Magn. Reson. Chem. 2020, 58(9), 880–888.

17. Monitoring real‐time curing of epoxies in situ using single‐sided NMR

Kelley, M.; Abdol, N.; Soroushian, P.; Keating, K.; Balachandra, A. M.; Meldrum, T. J. Polym. Sci. 2020, 58, 616–623.

16. Revealing the distribution of metal carboxylates in oil paint from the micro- to nanoscale

Ma, X.; Beltran, V.; Ramer, G.; Pavlidis, G.; Parkinson, D. Y.; Thoury, M.; Meldrum, T.; Centrone, A.; Berrie, B. Angew. Chem. Int. Ed. 2019, 58, 11652–11656.

15. Probing molecular dynamics with hyperpolarized ultrafast Laplace NMR using a low-field, single-sided magnet

King, J. N.; Fallorina, A.; Yu, J.; Zhang, G.; Telkki, V.-V.; Hilty, C; Meldrum, T. Chem. Sci. 2018, 9, 6143–6149.

14. Spatially Resolved Measurements of Crosslinking in UV-Curable Coatings Using Single-Sided NMR

Brass, M.; Morin, F.; Meldrum, T. Magnetochemistry 2018, 4(1), 8.

13. Automatizing the Comparison of NMR Depth Profiles

Rehorn, C.; Kehlet, C.; Del Federico, E.; Zia, W.; Meldrum, T.; Blümich, B. Strain 2017, e12254.

12. Physical and chemical properties of traditional and water-mixable oil paints assessed using single-sided NMR

Udell, N. A.; Hodgkins, R. E.; Berrie, B. H.; Meldrum, T. Microchem. J. 2017, 133, 31–36.

11. Evidence for the Accumulative Effect of Organic Solvent Treatments on Paintings and What to Do about It: A Case Study of Two “Identical” Seventeenth-Century Paintings Using Single-Sided Nuclear Magnetic Resonance

Fife, G.; Stabik, B.; Blümich, B.; Hoppenbrouwers, R.; Meldrum, T. ; In The Noninvasive Analysis of Painted Surfaces: Scientific Impact and Conservation Practice; Nevin, A. and Doherty, T., Eds. Smithsonian Contribution to Museum Conservation 2016, 5(5), 15–23.

10. Ultrafast Multidimensional Laplace NMR Using a Single-sided Magnet

King, J. N.; Lee, V. J.; Ahola, S.; Telkki, V-V.; Meldrum, T. Angew. Chemie Int. Ed. 2016, 55, 5040–5043.

9. Characterization of aging and solvent treatments of painted surfaces using single-sided NMR

Fife, G.; Stabik, B.; Kelley, A. E.; King, J. N.; Blumich, B.; Hoppenbrouwers, R.; Meldrum, T. Magn. Reson. Chem. 2014, 53, 58–63.

8. Hyperpolarized Xenon-Based Molecular Sensors for Label-Free Detection of analytes

Garimella, P. D.; Meldrum, T.; Witus, L. S.; Smith, M.; Bajaj, V S.; Wemmer, D. E.; Francis, M. B.; Pines, A. J. Am. Chem. Soc. 2014, 136, 164–168.

7. Nondestructive Investigation of the Internal Structure of Fresco Paintings. (In 2013 Digital Heritage International Congress DigitalHeritage)

Fukunaga, K.; Meldrum, T.; Zia, W.; Ohno, M.; Fuchida, T.; Blumich, B. IEEE 2013, 1, 81–88.

6. Band-Selective Chemical Exchange Saturation Transfer Imaging with Hyperpolarized Xenon-Based Molecular Sensors

Meldrum, T.; Bajaj, V. S.; Wemmer, D. E.; Pines, A. J. Magn. Reson. 2011, 13, 14–21.

5. Xenon-Based Molecular Sensors in Lipid Suspensions

Meldrum, T.; Schröder, L.; Denger, P.; Wemmer, D. E.; Pines, A. J. Magn. Reson. 2010, 205, 242–246. (Cover article.)

4. A Xenon-Based Molecular Sensor Assembled on an MS2 Viral Capsid Scaffold

Meldrum, T.; Seim, K. L.; Bajaj, V. S.; Palaniappan, K. K.; Wu, W.; Francis, M. B.; Wemmer, D. E.; Pines, A. J. Am. Chem. Soc. 2010, 132, 5936–5937.

3. Xenon Biosensors for Multi-Purpose Molecular Imaging (World Congress on Medical Physics and Biomedical Engineering)

Schröder, L.; Meldrum, T.; Smith, M.; Schilling, F.; Denger, P.; Zapf, S.; Wemmer, D. E.; Pines, A. September 7–12, 2009, Munich, Germany. IFMBE Proc. 2009, 25/13, 176–179.

2. Temperature-Controlled Molecular Depolarization Gates in Nuclear Magnetic Resonance

Schröder, L.; Chavez, L.; Meldrum, T.; Smith, M.; Lowery, T. J.; Wemmer, D. E.; Pines, A. Angew. Chem. Int. Ed. 2008, 47, 4316–4320. (Frontispiece.)

1. Temperature Response of ¹²⁹Xe Depolarization Transfer and Its Application for Ultrasensitive NMR Detection

Schröder, L.; Meldrum, T.; Smith, M.; Lowery, T. J.; Wemmer, D. E.; Pines, A. Phys. Rev. Lett. 2008, 100, 257603(4).

Talks

Teaching

Service and leadership

• Currently signed in to 43 different slack teams